Thomas Calzascia, Marc Pellegrini, Albert Lin, Kristine M. Garza, Alisha R. Elford, Arda Shahinian, Pamela S. Ohashi, Tak W. Mak Proceedings of the National Academy ...

Professors Yao Yongming and Du Xiaohui, leading a research group at the Chinese PLA General Hospital, have published groundbreaking findings demonstrating that CD4+ T lymphocytes undergo PANoptosis ...

Researchers at Brigham and Women's Hospital (BWH) have discovered a new cellular and molecular pathway that regulates CD4+ T cell response--a finding that may lead to new ways to treat diseases that ...

Remarkably, blood CD4 T cells are resistant to this death pathway, in part because the cells are in a deeper state of rest, meaning the virus is unable to infect them completely, which prevents the ...

CD4+ T cells, or helper T cells, are one type of lymphocyte that helps coordinate the immune response against infection and disease. They interact and activate other cells in the immune system. The ...

Studies presented here show that the expression of CD4, MHC class II (Ia,) and B220 cleanly resolves a major and a minor subset within the earliest pro-B cell population (germ-line pro-B) in adult ...

Idiopathic CD4 lymphocytopenia (ICL) is a clinical syndrome that is defined by CD4 lymphopenia of less than 300 cells per cubic millimeter in the absence of any primary or acquired cause of ...

Researchers may have discovered a second molecular 'switch' that turns off the immune system's response against HIV. Last year the same team identified a molecule that suppresses the activity of ...

T cell maturation is dependent on the intrathymic proliferation, survival and differentiation of precursor cells. These processes are regulated to a large extent by signals received through the pre-T ...

The word sting is usually associated with a quick sharp pain or hurt, but sting may now be associated with protection. Researchers from the Sylvester Comprehensive Cancer Center at the University of ...