The ability of mutations to cause cancer depends on how fast they force cells to divide, Sinai Health researchers have found. The study, led by Dr. Rod Bremner, a Senior Investigator at the ...

Researchers at The Institute of Cancer Research, London identified the CIP2A–TOPBP1 complex as a master regulator of DNA repair during mitosis, coordinating backup pathways that protect chromosomes ...

The review emphasizes how breakthroughs in understanding the molecular mechanisms of cell cycle regulation have paved the way for the development of targeted anti-cancer agents. Notably, inhibitors of ...

Preclinical AML studies showed palbociclib plus venetoclax produced stronger, more durable anti‑leukemia activity than venetoclax alone and may overcome resistance.

Neoantigens are unique markers that distinguish only cancer cells. By adding B cell reactivity, cancer vaccines can move ...

Inside the human airway, a certain cell type reigns supreme: multiciliated cells, decorated with dozens of hair-like cilia all beating in tandem. These cells are responsible for clearing out foreign ...

“We are encouraged by the emerging data from our lung cancer programs, where systemically delivered Olvi-Vec continues to ...