A research-driven evaluation assessing the comparative effectiveness of phosphodiesterase type 5 (PDE5) inhibitors is contributing to ongoing clinical discourse around vascular-mediated functional ...

Comparative effectiveness research has been the target of recurrent criticism in some political circles, with opponents claiming it’s the “gateway to rationing” or it encourages “cookbook medicine.” ...

Cancer is extremely political and extremely emotional. That makes a discussion on the economics of cancer treatment tricky. Further, the cost and value of cancer therapies are not discussed properly.

Ellen-Marie Whelan discusses why we need evidence-based health care, how it will improve health, and how we can promote it. The positions of American Progress, and our policy experts, are independent, ...

This effort to accelerate development can be clearly seen in how the agency is approaching biosimilars. In October 2025, the FDA issued a guidance update indicating that “switching” studies — a trial ...

This is a comparative effectiveness study that evaluates the safety effects of 2 types of commercially available electronic prescribing systems. The increasingly widespread adoption of electronic ...

A Comparative Effectiveness Research (CER) study shows that surgery is better than medical treatment for a particular cardiac condition. My patient is 78 years old and has complicated diabetes. – does ...

Issue brief from Ellen-Marie Whelan and Sonia Sekhar explains how comparative effectiveness research will help deliver better health care. When consumers shop for most products in America, we have the ...

For those expecting medical spending to ride out the coming recession, a new Congressional Budget Office study should give you pause. The study's conclusion sounds simple and non-controversial: Better ...

In a recent scientific paper published in the journal Nature Microbiology, researchers reproduced two target trials using electronic health records (EHRs) of the Department of Veterans Affairs (VA) to ...