All life on Earth rests on the same foundation: a four-letter genetic alphabet spelling out a repertoire of three-letter words that specify 20 amino acids. These basic building blocks—the components ...
A game-changining achievement in genome science has identified over 140,000 distinct DNA loops in our cells, providing chromosome fold resolution that is among the best ever created. In this ongoing ...
The ongoing fight of science against cancer has made great strides, but cancer cells have not made it easy. The complexity of cancer cells and their adaptive evolutionary nature complicate the search ...
Inside every human cell, six feet of DNA folds into a nucleus that is only a few micrometers wide, yet still manages to switch genes on and off with exquisite precision. The latest work on ...
Researchers at the CNIO show that oestrogens regulate gene expression by changing DNA supercoiling. Hormone-activated ...