A Northwestern Medicine study has revealed a previously unknown connection between two fundamental cellular processes, ...

Researchers at The Institute of Cancer Research, London identified the CIP2A–TOPBP1 complex as a master regulator of DNA repair during mitosis, coordinating backup pathways that protect chromosomes ...

DNA replication is a fundamental process essential for bacterial growth and survival. Initiation begins at the chromosomal origin (oriC), where the conserved initiator protein DnaA assembles into an ...

In a twist on the question, 'Which came first, the chicken or the egg?', scientists have long faced a similar question about how human adenovirus replicates: 'Which comes first, assembly of the viral ...

Learn how a newly discovered virus disrupts its host’s nucleus in ways that echo how complex cells may have formed billions ...

DNA doesn’t just sit still inside our cells — it folds, loops, and rearranges in ways that shape how genes behave.

“Our lab is generally interested in discovering and characterizing previously unknown or poorly understood factors that are essential for genome maintenance. This is particularly important in the ...

New work shows that physical folding of the genome to control genes located far away may have been a critical turning point for life on Earth. For evolutionary biologists, what most distinguishes the ...

In a twist on the question, "Which came first, the chicken or the egg?", scientists have long faced a similar question about how human adenovirus replicates: "Which comes first, assembly of the viral ...