The prevalence of serious inflammatory safety issues such as cytokine release syndrome and immune effector cell–associated ...
Cell cycle checkpoint-related genes (CCCRGs) are implicated in the development and progression of hepatocellular carcinoma ...
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CAR7 gene therapy shows promise in T-cell ALL
The use of base editing to generate universal off-the-shelf CAR T cells induced durable remissions -- up to 36 months in one ...
Immune effector cell-associated neurotoxicity syndrome (ICANS) is a possible side effect of certain immunotherapies. This condition causes inflammation in the brain, leading to symptoms. ICANS is a ...
The study, "A transcriptionally distinct subset of influenza-specific effector memory B cells predicts long-lived antibody responses to vaccination in humans,” was published in Immunity. “Our study ...
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Race for the Rheum Disease Cure Heats Up
For starters, she pointed out that standard CAR-T therapy involves a lymphodepletion regimen with cyclophosphamide and ...
In patients with relapsed or refractory systemic lupus erythematosus, allogeneic CAR-NK cell therapy may offer a safe treatment option and sustained efficacy, as shown in a first-in-human study.
Scientists have discovered that our specialized immune cells, called T cells, are what they eat -- their switch from functional to 'exhausted' depends on the switch from metabolizing acetate to ...
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