While intron retention (IR) is considered a widely conserved and distinct mechanism of gene expression control, its regulation is poorly understood. Here we show that DNA methylation directly ...
During RNA maturation, the group I intron promotes two sequential phosphorotransfer reactions resulting in exon ligation and intron release. Here, we report the crystal structure of the intron in ...
The dystrophin gene, which is mutated in Duchenne muscular dystrophy, is the largest human gene. A full spectrum of the gene transcripts has not been fully elucidated yet, although two cryptic exons ...
This is a preview. Log in through your library . Abstract RNA is commonly believed to undergo a number of sequential folding steps before reaching its functional fold, i.e., the global minimum in the ...
Researchers at University of Tsukuba have decoded the nuclear genome of Amorphochlora amoebiformis, a unicellular marine alga ...
Proper expression of proteins in eukaryotic cells requires precise stitching of protein-coding fragments, or exons, from precursor mRNAs that also contain non-coding introns. This process, known as ...
What if you could flip a genetic switch to silence a gene, then turn it back on with a simple drug? For researchers, gene-switch tools offer that kind of control—and a new system called Cyclone may ...
IIIF provides researchers rich metadata and media viewing options for comparison of works across cultural heritage collections. Visit the IIIF page to learn more. Intron A is an injectible recombinant ...
Some results have been hidden because they may be inaccessible to you
Show inaccessible results
Feedback