Figure 1: The G-quadruplex structure-specific antibody, BG4, binds with high affinity to RNA G-quadruplex structures. Here we show that a G-quadruplex-specific antibody, BG4 (ref. 4), binds to RNA ...
A collaboration led by Distinguished Professor Dr. Kazunori Ikebukuro from Tokyo University of Agriculture and Technology (TUAT), Japan, discovered that G-quadruplex (G4)-forming DNA binds myoglobin ...
The G-quadruplex is an alternative DNA structural motif that is considered to be functionally important in the mammalian genome for transcriptional regulation, DNA replication and genome stability, ...
DNA, the genetic material compacted in chromosomes, stores information to regulate all the cell processes in the body. Two decades ago, in addition to the widely known Watson-Crick double helix model ...
This is a preview. Log in through your library . Abstract The mouse hypervariable minisatellite (MN) Pc-1 consists of tandem repeats of d(GGCAG) and flanked sequences ...
IN 1962, when David R. Davies was in his 30s, he and two coworkers at the National Institutes of Health proposed that short, guanine-rich stretches of DNA could assume unusual structures. On the basis ...
Biomedical researchers studying aging and cancer are intensely interested in telomeres, the protective caps on the ends of chromosomes. In a new study, scientists at UC Santa Cruz used a novel ...
In work with potential implications for the development of anticancer therapeutics, the folding pattern of DNA quadruplexes formed by human telomeres in a solution of potassium ions, a medium closely ...
Guanine quadruplexes (G-quadruplexes or G4s) are unusual nucleic acid structures with distinct biological and chemical functions. They have occupied significant attention in the nucleic acid world ...
Martin Read, R. John Harrison, Barbara Romagnoli, Farial A. Tanious, Sharon H. Gowan, Anthony P. Reszka, W. David Wilson, Lloyd R. Kelland, Stephen Neidle Proceedings ...
Biomolecular self-assembly is a topic of current research interest consequent to biological function, therapeutics, biosensor applications, and biotechnological materials. Understanding self-assembly ...
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