Organoid models of the small intestines are now a closer match to the cellular architecture of the human intestine, thanks to the work done by the Organoid group at Hubrecht Institute in the ...

Researchers have discovered a way to help aging intestines heal themselves using CAR T-cell therapy. By targeting senescent ...

To better understand our organs and perform tests on a more human-like proxy, researchers are increasingly turning to organoids: miniaturized tissue cultures, usually in the form of organs, that are ...

Researchers from the Organoid group (formerly the Clevers group) have improved human small intestinal organoids – miniature versions of the small intestine. This will help them to better study the ...

The human gastrointestinal tract is in a constant state of flux; it hosts a diverse and dynamic community of microbes known as the gut microbiome, and is constantly exposed to things in the ...

Researchers have found that CAR T-cell therapy can help aging intestines heal by targeting senescent cells. In mice, it ...

Intestinal tuft cells divide to make new cells when immunological cues trigger them. Additionally, in contrast to progenitor- and stem cells, tuft cells can survive severe injury such as irradiation ...

Thanks to lab-grown miniature intestines, researchers at Uppsala University have successfully mapped how aggressive Shigella bacteria infect the human gut. The study opens the door to using cultured ...

Tuft cells are present throughout the intestinal tract as well as in many organs. Studies in mice have shown that when tuft cells sense the presence of pathogens, they signal to immune cells and to ...

Organ-Chips as a Platform for Studying Effects of Space on Human Enteric Physiology (Gut on Chip) examines the effect of microgravity and other space-related stress factors on biotechnology company ...