The proposed designs were then synthesised and tested in the lab where they achieved enzymatic activities close to those found in nature. ‘They’re not the best enzymes that have ever existed in nature ...

Designing de novo proteins holds immense potential for achieving superior combinations of novel functions and mechanical properties, thereby advancing biological and engineering applications. However, ...

For the field of drug development, hitting the right target with atomic precision to achieve therapeutic effect remains the core challenge. While traditional R&D pipelines are dependent on ...

The researchers feed these images into a generative diffusion model, which gradually adds noise until each image becomes all noise. The model tracks how the images become noisier and then runs the ...

Two groups have announced powerful new generative models that can design new proteins on demand not seen in nature. The explosion in text-to-image AI models like OpenAI’s DALL-E 2—programs trained to ...

For numerous fundamental processes of life, the formation of certain protein patterns is essential. Protein pattern formation controlled by molecular switches is—like many processes in nature—far ...

Gero, a biotechnology company developing novel therapeutics for aging and chronic diseases, has released ProtoBind-Diff, a novel masked diffusion language model that generates drug-like molecules for ...

Researchers have developed an artificial intelligence system that can create proteins not found in nature using generative diffusion, the same technology behind popular image-creation platforms such ...

Remember when predicting protein shapes using AI was the breakthrough of the year? That’s old news. Having solved nearly all protein structures known to biology, AI is now turning to a new challenge: ...

This is the third in a three-part series from Medscape on the impact of AI on drug discovery and development. Part 1 is about AI's role in designing speedier, more effective clinical trials. Part 2 is ...