Why do some people with amyloid plaques decline, while others do not? In the May 29 Nature Medicine, researchers led by Tharick Pascoal at the University of Pittsburgh laid some of the blame on ...

When astrocytes transform from homeostatic to reactive, what goes wrong inside them? Martin Kampmann, University of California, San Francisco, and colleagues blame dysfunctional lysosomes. In a ...

Researchers headed by a team at the Institute for Basic Science’s Center for Cognition and Sociality in South Korea reported on a discovery that they claim could revolutionize the diagnosis and ...

Astrocytes are critical for neurons and engage in a specific reactive response in Huntington’s disease. Astrocyte reactivity is being revealed as a heterogeneous and functionally powerful component of ...

Astrocytes, the predominant glial population in the human central nervous system, play crucial roles in neuroprotection, immunity, and homeostasis. However, when exposed to certain neuroinflammatory ...

PET imaging of reactive astrocyte-neuron interaction reveals new insights into Alzheimer's disease pathology, offering a potential breakthrough in diagnosis and treatment Recently, a team of South ...

Glioblastoma multiforme (GBM) is the most aggressive form of brain cancer with a short median survival time. GBM is characterized by the hallmarks of aggressive proliferation and cellular infiltration ...

In a recent review published in Experimental & Molecular Medicine, researchers reviewed existing data on the neurodegenerative effects of astrocyte-derived lipocalin-2 (LCN-2). Study: Lipocalin-2: a ...

A new platform for screening astrocyte reactivity helps researchers uncover potential therapeutic interventions to treat neurodegenerative conditions. Led by postdoctoral researcher Benjamin Clayton, ...

A breakthrough new Alzheimer’s disease treatment is stopping neurodegeneration in its tracks, even before symptoms appear.