Researchers discover a unique genetic code in Antarctic archaea that encodes a rare amino acid, potentially advancing protein ...

A new study finds that at least one Archaea has surprisingly flexibility when interpreting genetic code, which goes against a ...

Hidden within the genetic code lies the "triplet code," a series of three nucleotides that determine a single amino acid. How did scientists discover and unlock this amino acid code? Once the budding ...

The code of life is simple. Four genetic letters arranged in triplets—called codons—encode amino acids. These are the building blocks of proteins, the machinery that powers life. But the genetic code ...

This important study introduces a new biology-informed strategy for deep learning models aiming to predict mutational effects in antibody sequences. It provides solid evidence that separating ...

To overcome the inherent challenge of translation termination interference caused by stop codon reprogramming in mammalian cells, researchers from Peking University led by Chen Peng from College of ...

Scientists trying to engineer biologic molecules with new functions have long felt limited by the 20 amino-acid building blocks. Researchers are working to develop ways of putting new building ...

It's a dogma taught in every introductory biology class: Proteins are composed of combinations of 20 different amino acids, arranged into diverse sequences like words. But researchers trying to ...

This study offers important insight into the pathogenic basis of intragenic frameshift deletions in the carboxy-terminal domain of MECP2, which account for some Rett syndrome cases, yet similar ...

This circular diagram represents the genetic code, showing how the four nucleotide bases of RNA (adenine [A], cytosine [C], guanine [G], and uracil [U]) form codons that specify amino acids. Each ...