The application of mass-spectrometry-based proteomics to profiling whole organs or tissues requires that the samples be fractionated to increase the detection limits of analysis 1,2,3,4. We have ...

Researchers have developed a new pH probe and imaging technique to provide researchers more information when studying diseases like cancer and Alzheimer's. In the field of scientific research, details ...

Using a high-throughput fluorescence microscopy system and machine learning algorithms, oxidative stress-related changes in protein localization have been mapped by researchers from Japan. Furthermore ...

Just like workers need the right environment to efficiently perform their tasks, proteins require placement within specific cellular compartments to function properly. Therefore, understanding where ...

Researchers can now rapidly isolate and chemically characterize individual organelles within cells. The new technique tests the limits of analytical chemistry and rapidly reveals the chemical ...

Super-resolution microscopy, or nanoscopy, enables the use of fluorescent-based molecular localization tools to study molecular structure at the nanoscale level in the intact cell. Analysis of ...

Researchers have revealed the structural underpinnings of memory formation across a broad network of neurons in the mouse brain. This work sheds light on the fundamentally flexible nature of how ...