Proceedings of the National Academy of Sciences of the United States of America, Vol. 115, No. 22 (May 29, 2018), pp. E5193-E5202 (10 pages) Store-operated Orai1 channels are activated through a ...
B lymphocytes have the ability to sense thousands of structurally different antigens and produce cognate antibodies against these molecules. For this they carry on their surface multiple copies of the ...
A crucial step in preclinical drug development is the confirmation of the novel therapeutic molecule's specific binding to the targeted protein. Transmembrane proteins (TPs) like ion channels, ...
Effect of TT-816, a novel immune response modifier targeting cannabinoid CB2 receptor, on antitumor immunity and cancer growth. Antitumor mechanisms of OncoTherad (MRB-CFI-1) nanoimmunotherapy ...