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What are NFL best bets for Week 15? We asked our experts for top predictions, player props

The holiday season is in full swing, and the USA TODAY Sports staff is in the spirit of giving.

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· 21h · on MSN

Sports betting roundup: NFL favorites deliver for bettors in Week 15

NFL Week 15 score picks, game predictions for who wins NFL games today

SF extends win streak to 4 games

Titans vs 49ers box score, player stats, game stats, score summary

The Tennessee Titans earned a 37-24 loss to the San Francisco 49ers on Dec. 14 at Levi's Stadium.

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· 1d · on MSN

49ers win fourth consecutive game with 37-24 win over Titans

USA TODAY Touchdown Wire on MSN · 1d

49ers vs. Titans highlights: SF extends win streak to 4 games

Niners Wire · 1d

Best photos from 49ers vs. Titans in Week 15

Dec 14, 2025; Santa Clara, California, USA; San Francisco 49ers running back Christian McCaffrey (23) warms up prior to the first half against the Tennessee Titans at Levi's Stadium.

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Titans vs 49ers injury updates: Inactives mean bad news for QB Cam Ward

Titans' Jeffery Simmons records a sack, forced fumble and a TD catch in loss to 49ers

How PFF graded Brock Purdy, 49ers' position groups in Week 15 win over Titans

The offensive line gave quarterback Brock Purdy an average of 3.44 seconds to throw, the highest since Week 5 of the 2024 season.

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Titans' losing ways return as Cam Ward can't keep up with high-flying 49ers

Where 49ers sit in 2025 NFL Week 16 power rankings after win vs. Titans