Glaser has become a bigger star in the past year. She was the only woman on Billboard’s list of the top 10 highest-grossing tours of 2025. But also, in a lineup dominated by escapist family-friendly stand-ups (Nate Bargatze, Gabriel Iglesias), she might be the one whose material had the most bite.

"Yes, the Golden Globes — without a doubt the most important thing that's happening in the world right now," the comedian said during her opening monologue. "I'm Nikki Glaser, and just like Wicked, I'm back for a sequel." She later called out the big-budget sequel for being Wicked: For Money.