Complement Therapeutics GmbH (CTx), a clinical-stage biotechnology company developing next-generation therapeutics for complement-mediated diseases, today announced that the U.S. Food and Drug ...

The FDA granted fast track designation for CTx001, an investigational gene therapy candidate for geographic atrophy secondary ...

The complement system is an important part of the humoral immune defence in mammals that is formed by about 35 soluble and cell-surface proteins. Together these proteins enable the host to recognize ...

Complement component 3, often called C3, is an essential protein of the immune system. This protein plays a vital role in the body’s innate immune system, providing: the first line of defense against ...

The complement system maintains tissue homeostasis and integrity and forms the first central and immediately acting line of defence against invading infectious microorganisms. Complement activation ...

From football fields to military training grounds, head injuries are leaving lasting marks on the brain in ways we're only ...

Pegcetacoplan significantly reduces proteinuria in patients with recurrent C3 glomerulopathy, or primary immune-complex ...

A thoughtful compliment can make your day…unless it’s backhanded, of course. A complement (spelled with an “e” instead of an “i”) can also be a good thing, but in a much different way. What’s the ...

We introduce a human retinal pigmented epithelial (RPE) cell-culture model that mimics several key aspects of early stage age-related macular degeneration (AMD). These include accumulation of sub-RPE ...

In myasthenia gravis, complement plays a big role in what happens to the muscle end of the neuromuscular junction, explains Miriam Freimer, MD, an author on 5 abstracts presented at the recent 15th ...

When it comes to the English language, I'm confident no one meant to confuse us. There wasn't a panel of mean English teachers who sat around a table, finding ways to ...